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Anti-hbegf Antibody Fab (CAT#: MOM-18374-F(E))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human hbegf Antibody Fab Fragment MOM-18374-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment specifically binds to Human HBEGF, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • HBEGF
  • Type
  • Fab
  • Immunogen
  • Recombinant human HB EGF ectodomain expressed in SF21 cells.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
  • Function
  • epidermal growth factor receptor binding; eukaryotic cell surface binding; growth factor activity; heparin binding; receptor activity;
  • Synonyms
  • HBEGF; heparin-binding EGF-like growth factor; diphtheria toxin receptor (heparin binding epidermal growth factor like growth factor) , DTR, DTS, HEGFL; proheparin-binding EGF-like growth factor; Diphtheria toxin receptor (heparin binding EGF like growth factor); heparin binding epidermal growth factor; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DTS; DTSF; HEGFL

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